Mycosis fungoides

Mycosis fungoides was first described nearly 200 years ago, in a patient with large necrotic ‘mushroom-like’ tumours on the skin. Mycosis fungoides is now recognised to be the most common variant of a heterogeneous group of non-Hodgkin’s lymphomas that present in the skin: known as cutaneous T-cell lymphoma. This article will describe the epidemiology, clinical and histological features, staging, treatment and prognosis of mycosis fungoides and of its leukaemic variant, the Sézary syndrome.