Intended for healthcare professionals

Single gene disorders and dermatology

Jemima Mellerio
The last decade has witnessed phenomenal advances in our understanding of the molecular basis of an ever-increasing number of inherited diseases. To date, more than 1,000 different single-gene disorders have been characterised, of which more than 300 affect the skin or its appendages. This explosion of information has had a significant impact at a basic science level in unravelling much about the structure and function of normal skin, and has started to lead to more logical classification systems based on specific causative molecular pathology.
Dermatology in practice 2002; 10(1): 16–19
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Dermatology in practice was previously supported by Wyeth from 2008 to 2010, by Wyeth and Serono in 2007, by Wyeth and Shire from 2005 to 2006, by Medlock Medical in 2004 and by SSL International from 2001 to 2003.

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