Intended for healthcare professionals

Vitiligo – recent advances

Beth Collin and Irshad Zaki
The prevalence of vitiligo is estimated at between 0.5–1 % of the population with equal sex incidence. Around 50% of cases manifest before the age of 20 years. Vitiligo is a clinical diagnosis based on the appearance of chalk-white macules with well demarcated borders. Macules of depigmentation may appear anywhere on the body and lesions are often distributed symmetrically. The disease is classified according to its extent and distribution. The natural history of vitiligo is relatively poorly documented. The tendency is for lesions to expand with time and for new lesions to appear. In many patients, the disease stabilises and lesions become static. It is rare for lesions to spontaneously repigment.
Dermatology in practice 2003; 11(1): 28–30
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